Surgical Indication for Refractory Childhood Epilepsy

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چکیده

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Early prediction of refractory epilepsy in childhood

PURPOSE To investigate early predictors (6 months after diagnosis) of refractory epilepsy. METHODS STUDY DESIGN prospective cohort study. INCLUSION CRITERIA all consecutive children <14 years with two or more unprovoked seizures 24h apart, who were seen at our hospital between 1994 and 2004. EXCLUSION CRITERIA patients previously examined in other centres. DEFINITIONS refractory epil...

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Sleep-Related Seizures in Refractory Focal Epilepsy: Electroclinical Findings and Surgical Outcome

Background: Sleep Seizures (SSs) generally occur in refractory focal epilepsy, but their detailed characteristics and circadian patterns are still controversial. The effect of SSs on epilepsy surgery outcome has been addressed in few studies without definitive prognostic value.   Objectives: This study investigated the characteristics of SSs and their prognosis in refractory focal epilepsy. M...

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Response to sequential treatment schedules in childhood epilepsy Risk for development of refractory epilepsy

PURPOSE To investigate response to sequential treatment schedules and risk of development of refractory epilepsy in childhood. METHODS All children younger than 14 years with two or more unprovoked seizures seen at our hospital between 1994 and 2004 were included and prospectively followed. "Seizure control" was defined as a 2-year seizure-free interval without further recurrences except thos...

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A Treatable Refractory Epilepsy: A Case Report

Introduction Biotinidase deficiency is a life threatening inborn error of metabolism specially when delayed in diagnosis. We report a 2-month-old male infant that presented with refractory infantile spasm, alopecia and seborrheic dermatitis. With a high suspicion of the biotinidase deficiency we started biotin 10 mg daily orally before definite diagnosis was made. Rapid treatment was life-savin...

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ژورنال

عنوان ژورنال: Epilepsia

سال: 2000

ISSN: 0013-9580,1528-1167

DOI: 10.1111/j.1528-1157.2000.tb02214.x